Assessing encapsulation of curcumin in cocoliposome: In vitro study
Abstract: Curcumin has been known and used in the medical and industrial world. One way to improve its stability, bioavailability and its medical applications is using encapsulation method. In this research, we studied cocoliposome (coconut liposome) as the encapsulation material. The encapsulation efficiency (EE), loading capacity (LC), release rate (RR), as well as the free radical scavenging activity, measured by inhibition ratio (IR), of curcumin in encapsulation product were studied on varying cholesterol compositions and in simulated gastric fluid (SGF, pH 1.2) and simulated intestinal fluid (SIF, pH 7.4) conditions. We found that curcumin encapsulation in cocoliposome (CCL) formulation was influenced by cholesterol composition and pH conditions. The EE, LC and free radical scavenging activity diminished under both the SIF and SGF conditions when the cholesterol concentration enhanced. However, the RR increased as the cholesterol intensified. The condition to acquire the most favorable encapsulation parameter values was at 10% cholesterol composition. Furthermore, the IR results at 10% cholesterol concentration of CCL was 67.70 and 82.13% in SGF and SIF milieu, respectively. The CCL formulation thrived better under SIF conditions for free radical scavenging activities.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Assessing encapsulation of curcumin in cocoliposome: In vitro study ; volume:19 ; number:1 ; year:2021 ; pages:358-366 ; extent:9
Open chemistry ; 19, Heft 1 (2021), 358-366 (gesamt 9)
- Urheber
-
Hudiyanti, Dwi
Al Khafiz, Muhammad Fuad
Anam, Khairul
Siahaan, Parsaoran
Suyati, Linda
- DOI
-
10.1515/chem-2021-0036
- URN
-
urn:nbn:de:101:1-2410171541300.181842281869
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 15.08.2025, 07:20 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Hudiyanti, Dwi
- Al Khafiz, Muhammad Fuad
- Anam, Khairul
- Siahaan, Parsaoran
- Suyati, Linda
Ähnliche Objekte (12)
Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release
Understanding of Polydopamine Encapsulation of Hydrophobic Curcumin for Pleiotropic Drug Nanoformulation
Die Wirkung von Curcumin beim Rhabdomyosarkom in vitro
Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells
Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy
Antiparasitic Efficacy of Curcumin Against Besnoitia besnoiti Tachyzoites in vitro
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Macromolecular Cargo Encapsulation via In Vitro Assembly of Two‐Component Protein Nanoparticles
Investigations on the biological availability and avtivity of curcumin in vitro
In vitro study of parasite elimination and endothelial protection by curcumin : adjunctive therapy for cerebral malaria
Curcumin in neurology
Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release
Understanding of Polydopamine Encapsulation of Hydrophobic Curcumin for Pleiotropic Drug Nanoformulation
Die Wirkung von Curcumin beim Rhabdomyosarkom in vitro
Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells
Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy
Antiparasitic Efficacy of Curcumin Against Besnoitia besnoiti Tachyzoites in vitro
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Macromolecular Cargo Encapsulation via In Vitro Assembly of Two‐Component Protein Nanoparticles
Investigations on the biological availability and avtivity of curcumin in vitro
In vitro study of parasite elimination and endothelial protection by curcumin : adjunctive therapy for cerebral malaria
Curcumin in neurology
Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release
Understanding of Polydopamine Encapsulation of Hydrophobic Curcumin for Pleiotropic Drug Nanoformulation
Die Wirkung von Curcumin beim Rhabdomyosarkom in vitro
Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells
Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration
Reactive oxygen species/glutathione dual sensitive nanoparticles with encapsulation of miR155 and curcumin for synergized cancer immunotherapy
Antiparasitic Efficacy of Curcumin Against Besnoitia besnoiti Tachyzoites in vitro
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Macromolecular Cargo Encapsulation via In Vitro Assembly of Two‐Component Protein Nanoparticles
Investigations on the biological availability and avtivity of curcumin in vitro
In vitro study of parasite elimination and endothelial protection by curcumin : adjunctive therapy for cerebral malaria