Ectopic thyroid tissue in the breast: A case report

Abstract: Ectopic thyroid tissue is a rare condition manifested as the appearance of thyroid tissue outside the thyroid gland. Here, we report a case of ectopic thyroid tissue in the breast. A 48-year-old Chinese woman who was diagnosed with breast cancer received modified radical mastectomy. A thyroid tissue was found on subsequent pathological examination. The ectopic thyroid tissue was confirmed by immunohistochemistry staining of thyroid biomarkers, including thyroglobulin, thyroid transcription factor-1, and thyroid peroxidase. Currently, abnormal thyroid anlage descent is the main theory to explain ectopic thyroid tissue, especially lingual thyroid. However, it is far-fetched to explain the pathogenesis of ectopic thyroid tissues existed in organs or tissues far from thyroid such as iris, cardiac, pulmonary, duodenal, adrenal, and vertebral. Here, we reviewed the previous cases of ectopic thyroid tissue in breast and proposed a “entoderm migration” theory to explain distant ectopic thyroid tissues based on embryonic development perspective.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Ectopic thyroid tissue in the breast: A case report ; volume:18 ; number:1 ; year:2023 ; extent:5
Open life sciences ; 18, Heft 1 (2023) (gesamt 5)

Urheber
Gong, Zheng
Yang, Yan
Liu, Zegang

DOI
10.1515/biol-2022-0628
URN
urn:nbn:de:101:1-2023061414460221380483
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:48 MESZ

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Beteiligte

  • Gong, Zheng
  • Yang, Yan
  • Liu, Zegang

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