Gold‐Catalyzed Cycloisomerization of Sulfur Ylides to Dihydrobenzothiepines

Abstract: The metal‐promoted nucleophilic addition of sulfur ylides to π‐systems is a well‐established reactivity. However, the driving force of such transformations, elimination of a sulfide moiety, entails stoichiometric byproducts making them unfavorable in terms of atom economy. In this work, a new take on sulfur ylide chemistry is reported, an atom‐economical gold (I)‐catalyzed synthesis of dihydrobenzo[b]thiepines. The reaction proceeds under mild conditions at room temperature.

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• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Gold‐Catalyzed Cycloisomerization of Sulfur Ylides to Dihydrobenzothiepines ; volume:26 ; number:48 ; year:2020 ; pages:10972-10975 ; extent:4 ; Chemistry - a European journal ; 26, Heft 48 (2020), 10972-10975 (gesamt 4)

Contributors, Places and Time

• Creator: Knittl‐Frank, Christian ; Saridakis, Iakovos ; Stephens, Thomas ; Gomes, Rafael ; Neuhaus, James ; Misale, Antonio ; Oost, Rik ; Oppedisano, Alberto ; Maulide, Nuno

Further information

• DOI: 10.1002/chem.202000622
• URN: urn:nbn:de:101:1-2022060413355538598213
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.