Determination of the cavitation pressure threshold in focused ultrasound wave fields applied to sonosensitive, biocompatible nanoparticles for drug delivery applications
Abstract: Employing sonosensitive nanoparticles as carriers of active pharmaceutical ingredients emerges in ultrasonic Drug Delivery. Drug release can be initiated by focused ultrasound via the effect of inertial cavitation in certain target areas of particle loaded tissue. For stimulating inertial cavitation, a specific peak rarefaction pressure threshold must be exceeded. This pressure threshold has to be determined in order to estimate the risk of tissue damage during the drug release procedure. Therefore, this study provides a method to reliably verify the cavitation pressure threshold of sonosensitive and biocompatible nanoparticles
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Current directions in biomedical engineering. - 6, 3 (2020) , 539-542, ISSN: 2364-5504
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2021
- Creator
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George, Benedikt
Lehner, Markus
Fink, Michael
Rupitsch, Stefan Johann
Hiltl, Pia T.
Savšek, Ula
Lee, Geoffrey
Ermert, Helmut
- DOI
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10.1515/cdbme-2020-3138
- URN
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urn:nbn:de:bsz:25-freidok-1934259
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
- 15.08.2025, 7:24 AM CEST
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Associated
- George, Benedikt
- Lehner, Markus
- Fink, Michael
- Rupitsch, Stefan Johann
- Hiltl, Pia T.
- Savšek, Ula
- Lee, Geoffrey
- Ermert, Helmut
- Universität
Time of origin
- 2021
Other Objects (12)
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Investigation of the inertial cavitation activity of sonosensitive and biocompatible nanoparticles for drug delivery applications employing high intensity focused ultrasound
Investigation of Inertial Cavitation Induced by Modulated Focused Ultrasound Stimuli
Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption
Cavitation-threshold Determination and Rheological-parameters Estimation of Albumin-stabilized Nanobubbles
Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia
Biocompatible nanocarriers
Prototype of a Coupling Device to Investigate Focused Ultrasound-Induced Inertial Cavitation for Drug Delivery Applications
Generation and Evolution of Cavitation Bubbles in Volume Alternate Cavitation (VAC)
Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment
Memory-Effect on Acoustic Cavitation
Likely Cavitation in Stochastic Elasticity
Investigation of Inertial Cavitation of Sonosensitive and Biocompatible Nanoparticles in Flow - Through Tissue- Mimicking Phantoms Employing Focused Ultrasound
Investigation of the inertial cavitation activity of sonosensitive and biocompatible nanoparticles for drug delivery applications employing high intensity focused ultrasound
Investigation of Inertial Cavitation Induced by Modulated Focused Ultrasound Stimuli
Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption
Cavitation-threshold Determination and Rheological-parameters Estimation of Albumin-stabilized Nanobubbles
Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia
Biocompatible nanocarriers
Prototype of a Coupling Device to Investigate Focused Ultrasound-Induced Inertial Cavitation for Drug Delivery Applications
Generation and Evolution of Cavitation Bubbles in Volume Alternate Cavitation (VAC)
Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment
Memory-Effect on Acoustic Cavitation
Likely Cavitation in Stochastic Elasticity
Investigation of Inertial Cavitation of Sonosensitive and Biocompatible Nanoparticles in Flow - Through Tissue- Mimicking Phantoms Employing Focused Ultrasound
Investigation of the inertial cavitation activity of sonosensitive and biocompatible nanoparticles for drug delivery applications employing high intensity focused ultrasound
Investigation of Inertial Cavitation Induced by Modulated Focused Ultrasound Stimuli
Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption
Cavitation-threshold Determination and Rheological-parameters Estimation of Albumin-stabilized Nanobubbles
Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia
Biocompatible nanocarriers
Prototype of a Coupling Device to Investigate Focused Ultrasound-Induced Inertial Cavitation for Drug Delivery Applications
Generation and Evolution of Cavitation Bubbles in Volume Alternate Cavitation (VAC)
Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment
Memory-Effect on Acoustic Cavitation