Determination of the cavitation pressure threshold in focused ultrasound wave fields applied to sonosensitive, biocompatible nanoparticles for drug delivery applications
Abstract: Employing sonosensitive nanoparticles as carriers of active pharmaceutical ingredients emerges in ultrasonic Drug Delivery. Drug release can be initiated by focused ultrasound via the effect of inertial cavitation in certain target areas of particle loaded tissue. For stimulating inertial cavitation, a specific peak rarefaction pressure threshold must be exceeded. This pressure threshold has to be determined in order to estimate the risk of tissue damage during the drug release procedure. Therefore, this study provides a method to reliably verify the cavitation pressure threshold of sonosensitive and biocompatible nanoparticles
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Current directions in biomedical engineering. - 6, 3 (2020) , 539-542, ISSN: 2364-5504
- Ereignis
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Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
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2021
- Urheber
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George, Benedikt
Lehner, Markus
Fink, Michael
Rupitsch, Stefan Johann
Hiltl, Pia T.
Savšek, Ula
Lee, Geoffrey
Ermert, Helmut
- DOI
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10.1515/cdbme-2020-3138
- URN
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urn:nbn:de:bsz:25-freidok-1934259
- Rechteinformation
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 15.08.2025, 07:24 MESZ
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Beteiligte
- George, Benedikt
- Lehner, Markus
- Fink, Michael
- Rupitsch, Stefan Johann
- Hiltl, Pia T.
- Savšek, Ula
- Lee, Geoffrey
- Ermert, Helmut
- Universität
Entstanden
- 2021
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