Statistical primer: sample size and power calculations - why, when and how?

Abstract: When designing a clinical study, a fundamental aspect is the sample size. In this article, we describe the rationale for sample size calculations, when it should be calculated and describe the components necessary to calculate it. For simple studies, standard formulae can be used; however, for more advanced studies, it is generally necessary to use specialized statistical software programs and consult a biostatistician. Sample size calculations for non-randomized studies are also discussed and two clinical examples are used for illustration

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
European journal of cardio-thoracic surgery. - 54, 1 (2018) , 4-9, ISSN: 1010-7940

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2019
Creator
Hickey, Graeme L.
Grant, Stuart W.
Dunning, Joel
Siepe, Matthias
Contributor

DOI
10.1093/ejcts/ezy169
URN
urn:nbn:de:bsz:25-freidok-1467519
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:33 AM CEST

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Associated

Time of origin

  • 2019

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