Microwave-assisted one-pot syntheses of 4-aminoquinazolines

Abstract: A simple, environmentally friendly, one-pot method for the synthesis of 4-aminoquinazolines using microwave irradiation has been developed. Structures of derivatives 3, 4, and 5 were confirmed by single-crystal X-ray diffraction. The in vitro cytotoxicity of each compound was investigated using an MTT assay with A549 and HepG2 cell lines to calculate half-maximal inhibitory concentrations.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Microwave-assisted one-pot syntheses of 4-aminoquinazolines ; volume:5 ; number:3 ; year:2016 ; pages:247-252 ; extent:6
Green processing & synthesis ; 5, Heft 3 (2016), 247-252 (gesamt 6)

Creator
Song, Wenting
He, Shunli
Yuan, Zeli
Yu, Guangqing
Wu, Di
Wu, Qing
Zhang, Minqing
Chen, Yongzheng
Hu, Qinghong

DOI
10.1515/gps-2015-0121
URN
urn:nbn:de:101:1-2501120332360.440595095889
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.09.0011, 6:32 AM CET

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Associated

  • Song, Wenting
  • He, Shunli
  • Yuan, Zeli
  • Yu, Guangqing
  • Wu, Di
  • Wu, Qing
  • Zhang, Minqing
  • Chen, Yongzheng
  • Hu, Qinghong

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