The Discovery of Oral Cancer Prognostic Factor Ranking Using Association Rule Mining

Abstract: Objective A 5-year survival rate is a predictor for the assessment of oral cancer prognosis. The purpose of this study is to analyze oral cancer data to discover and rank the prognostic factors associated with oral cancer 5-year survival using the association rule mining (ARM) technique. Materials and Methods This study is a retrospective analysis of 897 oral cancer patients from a regional cancer center between 2011 and 2017. The 5-year survival rate was assessed. The multivariable Cox proportional hazards analysis was performed to determine prognostic factors. ARM was applied to clinicopathologic and treatment modalities data to identify and rank the prognostic factors associated with oral cancer 5-year survival. Results The 5-year overall survival rate was 35.1%. Multivariable Cox proportional hazards analysis showed that tumor (T) stage, lymph node metastasis, surgical margin, extranodal extension, recurrence, and distant metastasis of tumor were significantly associated with overall survival rate (p < 0.05). The top associated death within 5 years rule was positive extranodal extension, followed by positive perineural and lymphovascular invasion, with confidence levels of 0.808, 0.808, and 0.804, respectively. Conclusion This study has shown that extranodal extension, and perineural and lymphovascular invasion were the top ranking and major deadly prognostic factors affecting the 5-year survival of oral cancer.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
The Discovery of Oral Cancer Prognostic Factor Ranking Using Association Rule Mining ; day:14 ; month:05 ; year:2024
European journal of dentistry ; (14.05.2024)

Contributor
Chaowchuen, Sitthi
Warin, Kritsasith
Somyanonthanakul, Rachasak
Panichkitkosolkul, Wararit
Suebnukarn, Siriwan

DOI
10.1055/s-0043-1777050
URN
urn:nbn:de:101:1-2406271107092.470667446307
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:59 AM CEST

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Associated

  • Chaowchuen, Sitthi
  • Warin, Kritsasith
  • Somyanonthanakul, Rachasak
  • Panichkitkosolkul, Wararit
  • Suebnukarn, Siriwan

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