The DECON pilot project investigates predictive markers for successful bariatric surgery

Abstract: Obesity is a chronic, multifactorial disease which is linked to a number of adverse endocrinological and metabolic conditions. Currently, bariatric surgery is one of the most effective treatments for individuals diagnosed with severe obesity. However, the current indications for bariatric surgery are based on inadequate metrics (i.e., BMI) which do not account for the complexity of the disease, nor the heterogeneity among the patient population. Moreover, there is a lack of understanding with respect to the biological underpinnings that influence successful and sustained weight loss post-bariatric surgery. Studies have implicated age and pre-surgery body weight as two factors that are associated with favorable patient outcomes. Still, there is an urgent medical need to identify other potential factors that could improve the specificity of candidate selection and better inform the treatment plan of patients with obesity. In this report, we present and describe the cohort of the DECON pilot project, a multicenter study which aims to identify predictive biomarkers of successful weight loss after bariatric surgery

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch
Anmerkungen
Scientific reports. - 13, 1 (2023) , 13401, ISSN: 2045-2322

Ereignis
Veröffentlichung
(wo)
Freiburg
(wer)
Universität
(wann)
2023
Urheber
Seifert, Gabriel
Fagnocchi, Luca
Edozie, Michael
Herrmann, Stephan
Baumann, Hannah
Panzeri, Ilaria
Mewes, Stephanie
Aicher, David
Runkel, Mira
Läßle, Claudia
Fink, Jodok Matthias
Marjanovic, Goran
Fichtner-Feigl, Stephan
Pospisilik, J. Andrew

DOI
10.1038/s41598-023-40452-7
URN
urn:nbn:de:bsz:25-freidok-2408604
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:57 MESZ

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  • 2023

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