Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis

to related objects

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis ; volume:10 ; number:11 ; year:2018 ; extent:15
EMBO molecular medicine / European Molecular Biology Organization ; 10, Heft 11 (2018) (gesamt 15)

Creator: Civiletto, Gabriele
Dogan, Sukru Anil
Cerutti, Raffaele
Fagiolari, Gigliola
Moggio, Maurizio
Lamperti, Costanza
Benincá, Cristiane
Viscomi, Carlo
Zeviani, Massimo

DOI: 10.15252/emmm.201708799

URN: urn:nbn:de:101:1-2022083006220156437020

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:29 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Civiletto, Gabriele
Dogan, Sukru Anil
Cerutti, Raffaele
Fagiolari, Gigliola
Moggio, Maurizio
Lamperti, Costanza
Benincá, Cristiane
Viscomi, Carlo
Zeviani, Massimo

Other Objects (12)

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function

Metformin rescues rapamycin-induced mitochondrial dysfunction and attenuates rheumatoid arthritis with metabolic syndrome

TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer

A Zinc‐ and Calcium‐Rich Lysosomal Nanoreactor Rescues Monocyte/Macrophage Dysfunction under Sepsis

rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Rapamycin rescues mitochondrial dysfunction in cells carrying the m.8344A > G mutation in the mitochondrial tRNALys

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann–Pick type C1, and Batten disease

Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microglia

Critical role of ROCK1 in AD pathogenesis via controlling lysosomal biogenesis and acidification

The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neurons

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Related objects

Reset password