Point‐of‐Care Testing (POCT) Devices for DNA Detection: A Comprehensive Review

DNA chips play a crucial role in point‐of‐care diagnostics by enabling rapid and accurate detection of genetic information. These chips offer high sensitivity and selectivity, allowing for the identification of specific DNA sequences associated with diseases and pathogens. Integration into lab‐on‐chip platforms streamlines and miniaturizes diagnostic workflows, paving the way for cost‐effective, portable, and user‐friendly testing devices that can revolutionize healthcare delivery. In this review, a comprehensive description of the platforms utilized in DNA analysis, including microfluidic devices and integrated DNA chips, is provided. It explores the selection and immobilization of DNA probes for improved selectivity. Additionally, it covers diverse detection techniques such as optical detection (colorimetry and fluorescence) and electrochemical techniques. In these discussions, it is aimed to provide a thorough understanding of the current state of the art in DNA biosensor‐integrated lab‐on‐chip technology for point‐of‐care testing. The continued advancements in DNA chip technology hold immense promise for the development of next‐generation point‐of‐care diagnostics, where integrated sample preparation and rapid results generation can further enhance patient outcomes and contribute to the effective management of diseases.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Point‐of‐Care Testing (POCT) Devices for DNA Detection: A Comprehensive Review ; day:15 ; month:10 ; year:2023 ; extent:20
Advanced nanoBiomed research ; (15.10.2023) (gesamt 20)

Urheber
Mahardika, Ignasia Handipta
Naorungroj, Sarida
Khamcharoen, Wisarut
Kin, Sarath
Rodthongkum, Nadnudda
Chailapakul, Orawon
Shin, Kwanwoo

DOI
10.1002/anbr.202300058
URN
urn:nbn:de:101:1-2023101615175605425846
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:49 MESZ

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Beteiligte

  • Mahardika, Ignasia Handipta
  • Naorungroj, Sarida
  • Khamcharoen, Wisarut
  • Kin, Sarath
  • Rodthongkum, Nadnudda
  • Chailapakul, Orawon
  • Shin, Kwanwoo

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