Genetically Encoded Activators of Small Molecules for Imaging and Drug Delivery

Abstract: Chemical biologists have developed many tools based on genetically encoded macromolecules and small, synthetic compounds. The two different approaches are extremely useful, but they have inherent limitations. In this Minireview, we highlight examples of strategies that combine both concepts to tackle challenging problems in chemical biology. We discuss applications in imaging, with a focus on super‐resolved techniques, and in probe and drug delivery. We propose future directions in this field, hoping to inspire chemical biologists to develop new combinations of synthetic and genetically encoded probes.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Genetically Encoded Activators of Small Molecules for Imaging and Drug Delivery ; volume:132 ; number:20 ; year:2020 ; pages:7741-7749 ; extent:9
Angewandte Chemie ; 132, Heft 20 (2020), 7741-7749 (gesamt 9)

Creator
Thiel, Zacharias
Nguyen, Jade
Rivera-Fuentes, Pablo

DOI
10.1002/ange.201915521
URN
urn:nbn:de:101:1-2022053107294086097086
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:33 AM CEST

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