The effects of low-toxic herbicide Roundup and glyphosate on mitochondria

Abstract: The effects of pesticides on the health of non-target living organisms in agricultural areas are critically important aspects for their safe use. Their release into the environment is an inevitable aspect for predicting and evaluation of the risk of their application. Roundup, a glyphosate-based herbicide, has been designed as an effective pesticide against weeds and now is the most widely used agrochemicals around the world due to its highly specific action of the biosynthesis of certain amino acids in plants. Despite it is claimed to be low toxic for not-target organisms, due to its broad application Roundup and products of its degradation were detected in organisms of diverse animals and humans. In this review, we describe animal and human studies of general adverse effects of Roundup and its principal substance glyphosate with focus on endocrine disruption, oxidative stress and behavioral disorders. At mechanistic level, we focus on the potential toxicity of the herbicide Round.... https://www.excli.de/index.php/excli/article/view/4478

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: The effects of low-toxic herbicide Roundup and glyphosate on mitochondria ; volume:21 ; day:10 ; month:01 ; year:2022 ; EXCLI journal ; 21 (10.01.2022)

Contributors, Places and Time

• Creator: Strilbytska, Olha M. ; Tsiumpala, Sviatoslav A. ; Kozachyshyn, Ivanna I. ; Strutynska, Tetiana ; Burdyliuk, Nadia ; Lushchak, Volodymyr ; Lushchak, Oleh

Further information

• DOI: 10.17179/excli2021-4478
• URN: urn:nbn:de:101:1-2022021802142551544802
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:38 AM CEST