Concise Total Synthesis of (+)-Aphanorphine
A concise total synthesis of (+)-aphanorphine is described. The key features of the strategy include a Pd-catalyzed intermolecular trimethylenemethane [3+2]-cycloaddition to form ring C and a Co-catalyzed radical cyclization through a hydrogen-atom transfer to close ring B. The synthesis was completed in six steps.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Concise Total Synthesis of (+)-Aphanorphine ; volume:32 ; number:09 ; year:2021 ; pages:913-916
Synlett ; 32, Heft 09 (2021), 913-916
- Beteiligte Personen und Organisationen
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Wang, Cheng
Guan, Yukun
- DOI
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10.1055/s-0037-1610769
- URN
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urn:nbn:de:101:1-2022031211293935044609
- Rechteinformation
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Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:27 MESZ
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Beteiligte
- Wang, Cheng
- Guan, Yukun
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