Brazilian consensus for diagnosis, management and treatment of hereditary transthyretin amyloidosis with peripheral neuropathy: second edition

Abstract: Hereditary transthyretin amyloidosis with peripheral neuropathy (ATTRv-PN) is an autosomal dominant inherited sensorimotor and autonomic polyneuropathy with over 130 pathogenic variants identified in the TTR gene. Hereditary transthyretin amyloidosis with peripheral neuropathy is a disabling, progressive and life-threatening genetic condition that leads to death in ∼ 10 years if untreated. The prospects for ATTRv-PN have changed in the last decades, as it has become a treatable neuropathy. In addition to liver transplantation, initiated in 1990, there are now at least 3 drugs approved in many countries, including Brazil, and many more are being developed. The first Brazilian consensus on ATTRv-PN was held in the city of Fortaleza, Brazil, in June 2017. Given the new advances in the area over the last 5 years, the Peripheral Neuropathy Scientific Department of the Brazilian Academy of Neurology organized a second edition of the consensus. Each panelist was responsible for reviewing the literature and updating a section of the previous paper. Thereafter, the 18 panelists got together virtually after careful review of the draft, discussed each section of the text, and reached a consensus for the final version of the manuscript.

Objekt anzeigen

• Weitere Titel: Consenso brasileiro para o diagnóstico, manejo e tratamento da polineuropatia amiloidótica familiar associada à transtirretina: segunda edição
• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Brazilian consensus for diagnosis, management and treatment of hereditary transthyretin amyloidosis with peripheral neuropathy: second edition ; volume:81 ; number:03 ; year:2023 ; pages:308-321 ; Arquivos de neuro-psiquiatria ; 81, Heft 03 (2023), 308-321

Beteiligte, Orts- und Zeitangaben

• Beteiligte Personen und Organisationen: Pinto, Marcus Vinicius ; França, Marcondes Cavalcante ; Gonçalves, Marcus Vinicius Magno ; Machado-Costa, Marcela Câmara ; Freitas, Marcos Raimundo Gomes de ; Gondim, Francisco de Assis Aquino ; Marrone, Carlo Domenico ; Martinez, Alberto Rolim Muro ; Moreira, Carolina Lavigne ; Nascimento, Osvaldo J. M. ; Covaleski, Anna Paula Paranhos ; Oliveira, Acary Souza Bulle de ; Pupe, Camila Castelo Branco ; Rodrigues, Marcia Maria Jardim ; Rotta, Francisco Tellechea ; Scola, Rosana Herminia ; Marques, Wilson ; Waddington-Cruz, Márcia

Weitere Informationen

• DOI: 10.1055/s-0043-1764412
• URN: urn:nbn:de:101:1-2023060111301139305476
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.