Circumferential Endoscopic Submucosal Dissection for Barrett's Esophagus with Multifocal High-Grade Dysplasia

Abstract: A 54-year-old male presented with longstanding history of heartburn and regurgitation. Upper gastrointestinal endoscopy and biopsy performed at the previous center were suggestive of Barrett's esophagus with high-grade dysplasia (HGD). In view of dysplasia with underlying Barrett's esophagus, endoscopic submucosal dissection (ESD) was planned. Multifocal high-grade dysplasia with underlying Barrett's esophagus needs treatment to prevent invasive cancer. Surgery has been the conventional treatment but is associated with morbid complications and mortality. ESD has emerged as a treatment for HGD and superficial adenocarcinoma in Barrett's segment, but circumferential ESD is associated with risk of stricture formation. The present case highlights the role of image-enhanced endoscopy in identifying dysplasia in Barrett's esophagus and minimally invasive endoscopic techniques as an alternative to conventional surgical techniques and prophylactic measures needed to prevent post-ESD complications.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Circumferential Endoscopic Submucosal Dissection for Barrett's Esophagus with Multifocal High-Grade Dysplasia ; volume:15 ; number:04 ; year:2024 ; pages:250-253 ; Journal of Digestive Endoscopy ; 15, Heft 04 (2024), 250-253

Contributors, Places and Time

• Contributor: Gupta, Pankaj ; Singla, Vikas ; Singh, Pankaj ; Acharya, Kalpana ; Aggarwal, Komal ; Soni, Harish

Further information

• DOI: 10.1055/s-0044-1791953
• URN: urn:nbn:de:101:1-2502201018574.713173866427
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:36 AM CEST