One-pot, three-component, iron-catalyzed synthesis of benzimidazoles via domino C–N bond formation

Abstract: An efficient one-pot, three-component process for the synthesis of benzimidazole derivatives using a catalytic amount of Fe(III) porphyrin has been developed. The reaction proceeds via domino C–N bond formation and cyclization reactions of benzo-1,2-quinone, aldehydes and ammonium acetate as a nitrogen source to selectively produce benzimidazole. A number of benzimidazole derivatives have been synthesized using this method in high yields under mild reaction conditions

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
RSC advances. - 13, 35 (2023) , 24789-24794, ISSN: 2046-2069

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2023
Creator
Aboonajmi, Jasem
Mohammadi, Masoumeh
Panahi, Farhad
Aberi, Mahdi
Sharghi, Hashem

DOI
10.1039/d3ra04450e
URN
urn:nbn:de:bsz:25-freidok-2387177
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:56 AM CEST

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Associated

  • Aboonajmi, Jasem
  • Mohammadi, Masoumeh
  • Panahi, Farhad
  • Aberi, Mahdi
  • Sharghi, Hashem
  • Universität

Time of origin

  • 2023

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