Does HPA-axis activity mediate the relationship between obstetric complications and externalizing behavior problems? The TRAILS study

Journal article | Zeitschriftenartikel

To examine whether HPA-axis activity mediates the relationship between obstetric complications (OCs) and externalizing behavior problems, and to investigate whether this model is different for boys and girls. In a population-based cohort of 1,768 10- to 12-year-old early adolescents, we assessed the cortisol awakening response and evening cortisol levels. Externalizing behavior problems were assessed using the Child Behavior Checklist and the Youth Self-Report. OCs were retrospectively assessed in a parent interview. OCs significantly predicted externalizing behavior problems, but OCs did not predict HPA-axis activity. Thus, the mediation model was not supported. In addition to the relationship between HPA-axis activity and externalizing behavior problems, which is specific for girls, there is also a relationship between OCs and externalizing behavior problems. However, these two mechanisms are not related to each other indicating that HPA-axis activity is not a mediator in the relationship between OCs and externalizing behavior problems. Future research should focus on understanding the mechanism through which OCs cause externalizing behavior problems.

Object Details

• Extent: Seite(n): 565-573
• Language: Englisch
• Notes: Status: Postprint; begutachtet (peer reviewed)

References and Relationships

• Bibliographic citation: European Child & Adolescent Psychiatry, 18(9)

Classification and Topics

• Subject: Psychologie ; psychische Störungen, Behandlung und Prävention

Contributors, Places and Time

• Event: Geistige Schöpfung
• (who): Marsman, Rianne ; Rosmalen, Judith G. M. ; Oldehinkel, Albertine J. ; Ormel, Johan ; Buitelaar, Jan K.
• Event: Veröffentlichung
• (where): Deutschland
• (when): 2009

Further information

• DOI: https://doi.org/10.1007/s00787-009-0014-y
• URN: urn:nbn:de:0168-ssoar-202712
• Rights: GESIS - Leibniz-Institut für Sozialwissenschaften. Bibliothek Köln
• Last update: 21.06.2024, 4:26 PM CEST