Persistent Facial Blanching after Botulinum Toxin Injection

We report the case of a 38-year-old male patient who presented with blanching of the face after strenuous exercise or physical exertion. The symptoms regressed in a relaxed state. Three years before presentation, he underwent botulinum toxin injections in the affected areas of the face. Facial blanching is a rare side effect of botulinum toxin injection. The postulated pathophysiology involves different transmitters mainly acetylcholine as well as co-transmitters implicated in vasodilation. Usually, facial blanching resolves shortly after waning of the botulinum toxin. However, in our case, the symptoms persisted for a longer time. Till date, therapy options for post-botulinum facial blanching are lacking, mainly due to the temporary aspect of the disease.

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• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Persistent Facial Blanching after Botulinum Toxin Injection ; volume:14 ; number:2 ; year:2022 ; pages:253-257 ; extent:4 ; Case reports in dermatology ; 14, Heft 2 (2022), 253-257 (gesamt 4)

Contributors, Places and Time

• Creator: Mitri, Fouad ; Kälber, Katharina Anna ; Enk, Alexander H. ; Toberer, Ferdinand

Further information

• DOI: 10.1159/000525937
• URN: urn:nbn:de:101:1-2022092201052877144098
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.