Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1750-1326

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia ; volume:11 ; number:1 ; day:24 ; month:6 ; year:2016 ; pages:1-17 ; date:12.2016
Molecular neurodegeneration ; 11, Heft 1 (24.6.2016), 1-17, 12.2016

Creator: Holler, Christopher J.

Contributor: Taylor, Georgia
McEachin, Zachary T.
Deng, Qiudong
Watkins, William J.
Hudson, Kathryn
Easley, Charles A.
Hu, William T.
Hales, Chadwick M.
Rossoll, Wilfried
Bassell, Gary J.
Kukar, Thomas
SpringerLink (Online service)

DOI: 10.1186/s13024-016-0114-3

URN: urn:nbn:de:1111-2016082911362

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:49 AM CEST

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Associated

Holler, Christopher J.
Taylor, Georgia
McEachin, Zachary T.
Deng, Qiudong
Watkins, William J.
Hudson, Kathryn
Easley, Charles A.
Hu, William T.
Hales, Chadwick M.
Rossoll, Wilfried
Bassell, Gary J.
Kukar, Thomas
SpringerLink (Online service)

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Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia

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Other Objects (12)

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Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations

Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation

Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

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Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency

Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia

Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations

Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation

Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations

Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration

Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

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Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation

Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

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Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice

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