Synthesis of Bioactive Macrocycles Involving Ring-Closing Metathesis Strategy

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This review reports the synthesis of various bioactive macrocycles, involving ring-closing metathesis as a key step, developed since ca. 2000. These macrocycles exhibited biological activities such as antiviral, antifungal, antibacterial, and anticancer activities, and more. Thus, their syntheses and utilization are essential for both synthetic organic and medicinal chemists.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Synthesis of Bioactive Macrocycles Involving Ring-Closing Metathesis Strategy ; volume:07 ; number:02 ; year:2023 ; pages:209-242
SynOpen ; 07, Heft 02 (2023), 209-242

Contributor: Jahan, Nasrin
Ansary, Inul

DOI: 10.1055/s-0042-1751453

URN: urn:nbn:de:101:1-2023070610514945786617

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:52 AM CEST

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Jahan, Nasrin
Ansary, Inul

Other Objects (12)

Metathesis polymerization of cystine-based macrocycles

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Olefin metathesis – ring-closing reaction

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Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

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Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

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Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

Metathesis polymerization of cystine-based macrocycles

zweidimensionales bewegtes Bild

Olefin metathesis – ring-closing reaction

Hochschulschrift

Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

Highly Substrate‐Selective Macrocyclic Ring Closing Metathesis

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

Hochschulschrift

Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

Metathesis polymerization of cystine-based macrocycles

zweidimensionales bewegtes Bild

Olefin metathesis – ring-closing reaction

Hochschulschrift

Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

Highly Substrate‐Selective Macrocyclic Ring Closing Metathesis

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

Hochschulschrift

Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

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Synthesis of Bioactive Macrocycles Involving Ring-Closing Metathesis Strategy

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Other Objects (12)

Metathesis polymerization of cystine-based macrocycles

Olefin metathesis – ring-closing reaction

Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

Highly Substrate‐Selective Macrocyclic Ring Closing Metathesis

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

Metathesis polymerization of cystine-based macrocycles

Olefin metathesis – ring-closing reaction

Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

Highly Substrate‐Selective Macrocyclic Ring Closing Metathesis

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

Metathesis polymerization of cystine-based macrocycles

Olefin metathesis – ring-closing reaction

Synthesis of bioactive peptides and conformationally restricted analogs including ring closing metathesis : = Synthese von bioaktiven Peptiden und konformativ eingeschränkten Analoga inklusive Ring-Closing-Metathesis

Cyclopeptide Synthesis by Ring-Closing Metathesis

Highly Substrate‐Selective Macrocyclic Ring Closing Metathesis

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Selective Cross‐Metathesis Versus Ring‐Closing Metathesis of Terpenes, Taking the Path Less Travelled

Synthesis of Berkeleylactone A by Ring‐Closing Alkyne Metathesis

SPS of Seragamide A via Relay-Ring-Closing Metathesis

Ring closing metathesis : a gateway to medium size ring ethers

Constraining Peptide Conformations with the Help of Ring-Closing Metathesis

Diastereoselective Ring-Closing Metathesis to Build a Quaternary Carbon Center

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