From Cyclopropene to Housane Derivatives Via Intramolecular Cyclopropanation

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Abstract: The synthesis of housane derivatives from cyclopropenes is described. Under rhodium (II) catalysis, cyclopropenylvinyl carbinols can regioselectively generate a carbene intermediate which undergoes an intramolecular cyclopropanation to form a housane, a skeleton with similar ring strain as the cyclopropene precursor. The procedure shows a remarkable broad scope and efficiency. Moreover, the method served to prepare man‐made housane‐containing terpene derivatives, which are not accessible by Nature.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: From Cyclopropene to Housane Derivatives Via Intramolecular Cyclopropanation ; volume:63 ; number:46 ; year:2024 ; extent:6
Angewandte Chemie / International edition. International edition ; 63, Heft 46 (2024) (gesamt 6)

Creator: Coto, Darío
Suárez‐García, David
Mata, Sergio
Fernandez, Israel
López, Luis A.
Vicente, Rubén

DOI: 10.1002/anie.202409226

URN: urn:nbn:de:101:1-2411051314008.657440834951

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:26 AM CEST

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Associated

Coto, Darío
Suárez‐García, David
Mata, Sergio
Fernandez, Israel
López, Luis A.
Vicente, Rubén

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