Determining Ion‐Pair Binding Affinities of Heteroditopic Receptor Systems

Abstract: Determining ion‐pair affinities in heteroditopic receptor systems presents a persistent and significant challenge. The plethora of technical and experimental problems implicated in measuring ion‐pair affinities have encouraged the use of several expedient experimental practices as a means of characterising ion‐pair recognition behaviour. Exploiting a model heteroditopic receptor system, we interrogate the reliability of these methods and demonstrate that these commonly used techniques can be highly questionable and without extreme care can lead to incorrect conclusions.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Determining Ion‐Pair Binding Affinities of Heteroditopic Receptor Systems ; day:16 ; month:10 ; year:2024 ; extent:10
Chemistry - a European journal ; (16.10.2024) (gesamt 10)

Creator
Docker, Andrew
Min Tay, Hui

DOI
10.1002/chem.202402844
URN
urn:nbn:de:101:1-2410171420001.474430064125
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

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Associated

  • Docker, Andrew
  • Min Tay, Hui

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