A Case of Extensive Grover’s Disease in a Patient with a History of Multiple Non-Melanoma Skin Cancers

We report on a 69-year-old man who presented with itching and erythematous papules on his torso and extremities, which were resistant to topical therapy with antibiotics and steroids. Physical examination revealed multiple erythematous papules on his back, neckline, and lower extremities. The lesions had appeared 4 years earlier and usually worsened with heat or extensive sweating. Histopathology of previous skin biopsies had shown multiple cutaneous squamous cell carcinomas or was non-conclusive. Thus, a re-biopsy was performed, revealing acanthosis and focal acantholytic dyskeratosis. These clinical and anamnestic findings lead to the diagnosis of extensive Grover’s disease (GD). Oral therapy with isotretinoin 30-mg QD led to the regression of the skin lesions. Topical adapalene, as well as topical corticosteroids, were later prescribed for maintenance therapy.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: A Case of Extensive Grover’s Disease in a Patient with a History of Multiple Non-Melanoma Skin Cancers ; volume:13 ; number:3 ; year:2021 ; pages:553-557 ; extent:5 ; Case reports in dermatology ; 13, Heft 3 (2021), 553-557 (gesamt 5)

Contributors, Places and Time

• Creator: Kotzerke, Mareike ; Mitri, Fouad ; Enk, Alexander ; Toberer, Ferdinand ; Haenssle, Holger

Further information

• DOI: 10.1159/000519168
• URN: urn:nbn:de:101:1-2022011300060043579501
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:33 AM CEST