Peptide Bond Formation in the Protonated Serine Dimer Following Vacuum UV Photon‐Induced Excitation
Abstract: Possible routes for intra‐cluster bond formation (ICBF) in protonated serine dimers have been studied. We found no evidence of ICBF following low energy collision‐induced dissociation (in correspondence with previous works), however, we do observe clear evidence for ICBF following photon absorption in the 4.6–14 eV range. Moreover, the comparison of photon‐induced dissociation measurements of the protonated serine dimer to those of a protonated serine dipeptide provides evidence that ICBF, in this case, involves peptide bond formation (PBF). The experimental results are supported by ab initio molecular dynamics and exploration of several excited state potential energy surfaces, unraveling a pathway for PBF following photon absorption. The combination of experiments and theory provides insight into the PBF mechanisms in clusters of amino acids, and reveals the importance of electronic excited states reached upon UV/VUV light excitation.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Peptide Bond Formation in the Protonated Serine Dimer Following Vacuum UV Photon‐Induced Excitation ; day:03 ; month:03 ; year:2023 ; extent:6
Angewandte Chemie / International edition. International edition ; (03.03.2023) (gesamt 6)
- Urheber
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Licht, Ori
Barreiro‐Lage, Darío
Rousseau, Patrick
Giuliani, Alexandre
Milosavljević, Aleksandar R.
Isaak, Avinoam
Mastai, Yitzhak
Albeck, Amnon
Singh, Raj
Nguyen, Vy T. T.
Nahon, Laurent
Martínez‐Fernández, Lara
Díaz‐Tendero, Sergio
Toker, Yoni
- DOI
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10.1002/anie.202218770
- URN
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urn:nbn:de:101:1-2023030314450019647513
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:53 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Licht, Ori
- Barreiro‐Lage, Darío
- Rousseau, Patrick
- Giuliani, Alexandre
- Milosavljević, Aleksandar R.
- Isaak, Avinoam
- Mastai, Yitzhak
- Albeck, Amnon
- Singh, Raj
- Nguyen, Vy T. T.
- Nahon, Laurent
- Martínez‐Fernández, Lara
- Díaz‐Tendero, Sergio
- Toker, Yoni
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