Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- ISSN
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1465-542X
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
-
online resource.
- Bibliographic citation
-
Targeting SHP2 phosphatase in breast cancer overcomes RTK-mediated resistance to PI3K inhibitors ; volume:24 ; number:1 ; day:1 ; month:4 ; year:2022 ; pages:1-15 ; date:12.2022
Breast cancer research ; 24, Heft 1 (1.4.2022), 1-15, 12.2022
- Creator
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Heynen, Guus J. J. E.
Lisek, Kamil
Vogel, Regina
Wulf-Goldenberg, Annika
Alcaniz, Joshua
Montaudon, Elodie
Marangoni, Elisabetta
Birchmeier, Walter
- Contributor
-
SpringerLink (Online service)
- DOI
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10.1186/s13058-022-01521-3
- URN
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urn:nbn:de:101:1-2022062020594984523335
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:20 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Heynen, Guus J. J. E.
- Lisek, Kamil
- Vogel, Regina
- Wulf-Goldenberg, Annika
- Alcaniz, Joshua
- Montaudon, Elodie
- Marangoni, Elisabetta
- Birchmeier, Walter
- SpringerLink (Online service)
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Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
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The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
Characterisation and modulation of the phosphatase activity of phosphatase of regenerating liver-3 (PRL-3) and SH2 containing protein tyrosine phosphatase 2 (SHP2)
Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull’s eye for targeted therapy?
Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)
Tyrosine phosphatase SHP2 promoted the progression of CRC via modulating the PI3K/BRD4/TFEB signaling induced ferroptosis
Interaction of the disordered Gab1 with tyrosine phosphatase Shp2
RTK
Requirement of the tyrosine phosphatase Shp2 in mammary gland tumorgenesis in mice
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
Characterisation and modulation of the phosphatase activity of phosphatase of regenerating liver-3 (PRL-3) and SH2 containing protein tyrosine phosphatase 2 (SHP2)
Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull’s eye for targeted therapy?
Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)
Tyrosine phosphatase SHP2 promoted the progression of CRC via modulating the PI3K/BRD4/TFEB signaling induced ferroptosis
Interaction of the disordered Gab1 with tyrosine phosphatase Shp2
RTK
Requirement of the tyrosine phosphatase Shp2 in mammary gland tumorgenesis in mice
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells
The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
Characterisation and modulation of the phosphatase activity of phosphatase of regenerating liver-3 (PRL-3) and SH2 containing protein tyrosine phosphatase 2 (SHP2)
Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull’s eye for targeted therapy?