Fish oil and prevention of atrial fibrillation: An appraisal of the evidence

Atrial fibrillation (AF) is the most common cardiac arrhythmia. In the absence of optimal rhythm control therapy, due to lack of satisfaction of currently available membrane-acting antiarrhythmics and limited availability of ablative therapy, upstream therapies to prevent atrial fibrillation are emerging as a new pharmacologic strategy. Long chain n-3 (omega-3) polyunsaturated fatty acids (PUFAs) from fish have been suggested to account for these benefits. Multiple observational, clinical, and experimental studies have shown that regular fish consumption has a favorable effect on preventing AF. Experimental studies have shown a potential antiarrhythmic, antifibrotic and antiinflammatory effect of PUFAs on atrial tissues. This effect on the atrial substrate will lower atrial tissue vulnerability for development of atrial fibrillation. Recent prospective studies regarding the preventive benefit of PUFAs on post open-heart surgery AF showed mixed results. The purpose of this treatise is to review available studies of PUFA effects on AF and outline benefits of the PUFAs as an upstream therapy to prevent AF.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Fish oil and prevention of atrial fibrillation: An appraisal of the evidence ; volume:03 ; number:01 ; year:2011 ; pages:21-28 ; Ibnosina journal of medicine and biomedical sciences ; 03, Heft 01 (2011), 21-28

Beteiligte, Orts- und Zeitangaben

• Beteiligte Personen und Organisationen: Houmsse, Mahmoud ; Bazerbashi, Ayman ; Haykal, Kamal ; Mohammad, Marwan

Weitere Informationen

• DOI: 10.4103/1947-489X.210846
• URN: urn:nbn:de:101:1-2022071813401377096170
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:30 MESZ