HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) **

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Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) ** ; volume:21 ; number:23 ; year:2020 ; pages:3371-3376 ; extent:6
ChemBioChem ; 21, Heft 23 (2020), 3371-3376 (gesamt 6)

Creator: Schiedel, Matthias
Lehotzky, Attila
Szunyogh, Sandor
Oláh, Judit
Hammelmann, Sören
Wössner, Nathalie
Robaa, Dina
Einsle, Oliver
Sippl, Wolfgang
Ovádi, Judit
Jung, Manfred

DOI: 10.1002/cbic.202000351

URN: urn:nbn:de:101:1-2022061806362753761015

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:36 AM CEST

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Associated

Schiedel, Matthias
Lehotzky, Attila
Szunyogh, Sandor
Oláh, Judit
Hammelmann, Sören
Wössner, Nathalie
Robaa, Dina
Einsle, Oliver
Sippl, Wolfgang
Ovádi, Judit
Jung, Manfred

Other Objects (12)

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

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Proteolysis targeting chimeras (PROTACs) for epigenetics research

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Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

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Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

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Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

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Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

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Kinetische Untersuchungen humaner Sirtuin-Isoformen

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Design, Synthese und Charakterisierung neuer Sirtuin Inhibitoren

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Hochschulschrift

Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

Hochschulschrift

Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

Aufsatzsammlung

Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

Hochschulschrift

Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

Hochschulschrift

Kinetische Untersuchungen humaner Sirtuin-Isoformen

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Design, Synthese und Charakterisierung neuer Sirtuin Inhibitoren

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Hochschulschrift

Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

Hochschulschrift

Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

Aufsatzsammlung

Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

Hochschulschrift

Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

Hochschulschrift

Kinetische Untersuchungen humaner Sirtuin-Isoformen

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HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) **

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Other Objects (12)

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Design, Synthese und Charakterisierung neuer Sirtuin Inhibitoren

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

Kinetische Untersuchungen humaner Sirtuin-Isoformen

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Design, Synthese und Charakterisierung neuer Sirtuin Inhibitoren

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

Kinetische Untersuchungen humaner Sirtuin-Isoformen

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Design, Synthese und Charakterisierung neuer Sirtuin Inhibitoren

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Molecular Modelling Untersuchungen zum Bindungsverhalten von Histamin H2- und H3-Rezeptor-Liganden

Application of computer-based methods to guide the development of novel sirtuin inhibitors : [kumulative Dissertation]

Virtual screening and molecular modeling studies applied to discover novel sirtuin modulators and cholinesterase inhibitors : [kumulative Dissertation]

Epigenetic targets in drug discovery

Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

Investigations of sirtuin metabolism

Sirtuin 1 inhibiting thiocyanates (S1th) - a new class of isotype selective inhibitors of NAD+ dependent lysine deacetylases

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

Kinetische Untersuchungen humaner Sirtuin-Isoformen

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