Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase

to related objects

Abstract: 2‐Methylisoborneol is a widespread musty odourant that is produced by many bacteria including actinomycetes, cyanobacteria and myxobacteria. Two 2‐methylisoborneol synthases (MIBS) that are phylogenetically distant to the known enzyme from Streptomyces coelicolor were found to be highly active for 2‐methylisoborneol biosynthesis. Based on the enzyme structure and on an amino acid sequence alignment, the MIBS from S. coelicolor was extensively studied through site‐directed mutagenesis.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase ; day:20 ; month:04 ; year:2023 ; extent:10
Chemistry - a European journal ; (20.04.2023) (gesamt 10)

Creator: Gu, Binbin
Dickschat, Jeroen S.

DOI: 10.1002/chem.202300775

URN: urn:nbn:de:101:1-2023051715104641234214

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 11:02 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Gu, Binbin
Dickschat, Jeroen S.

Other Objects (12)

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Buchbeitrag

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Arbeitspapier

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Buchbeitrag

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Arbeitspapier

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Buchbeitrag

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Arbeitspapier

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Functional Characterisation of Highly Conserved and Structurally Prominent Residues of 2‐Methylisoborneol Synthase

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Combining specificity determining and conserved residues improves functional site prediction

Rapid functional diversification in the structurally conserved ELAV family of neuronal RNA binding proteins

Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains

Border areas in eastern Bavaria: Once structurally weak, always structurally weak?

Border areas in eastern Bavaria : Once structurally weak, always structurally weak?

Structurally Dependent Competing Risks

Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated “Entotheonella” Sponge Symbionts

Catalyst-free late-stage functionalization to assemble α-acyloxyenamide electrophiles for selectively profiling conserved lysine residues

Conserved residues within the HIV-1 Vpu transmembrane-proximal hinge region modulate BST2 binding and antagonism

Dual RNA-seq reveals distinct families of co-regulated and structurally conserved effectors in Botrytis cinerea infection of Arabidopsis thaliana

Related objects

Reset password