Metal‐Free Decarboxylative Allylation of Oxime Esters under Light Irradiation
Abstract: Allylation reactions, often used as a key step for constructing complex molecules and drug candidates, typically rely on transition‐metal (TM) catalysts. Even though TM‐free radical allylations have been developed using allyl‐stannanes, ‐sulfides, ‐silanes or ‐sulfones, much less procedures have been reported using simple and commercially available allyl halides, that are used for the preparation of the before‐mentioned allyl derivatives. Here, we present a straightforward photocatalytic protocol for the decarboxylative allylation of oxime esters using allyl bromide derivatives under metal‐free and mild conditions. This methodology yields a diverse variety of functionalized molecules including several pharmaceutically relevant molecules.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Metal‐Free Decarboxylative Allylation of Oxime Esters under Light Irradiation ; day:09 ; month:07 ; year:2024 ; extent:6
Chemistry - a European journal ; (09.07.2024) (gesamt 6)
- Creator
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Geniller, Lilian
Ben Kraim, Hiba
Clot, Eric
Taillefer, Marc
Jaroschik, Florian
Prieto, Alexis
- DOI
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10.1002/chem.202401494
- URN
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urn:nbn:de:101:1-2407101416399.078292336247
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:50 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Geniller, Lilian
- Ben Kraim, Hiba
- Clot, Eric
- Taillefer, Marc
- Jaroschik, Florian
- Prieto, Alexis
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Irradiation-induced palladium-catalyzed decarboxylative desaturation enabled by a dual ligand system
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