Metal‐Free Decarboxylative Allylation of Oxime Esters under Light Irradiation

zu Verbundenen Objekten

Abstract: Allylation reactions, often used as a key step for constructing complex molecules and drug candidates, typically rely on transition‐metal (TM) catalysts. Even though TM‐free radical allylations have been developed using allyl‐stannanes, ‐sulfides, ‐silanes or ‐sulfones, much less procedures have been reported using simple and commercially available allyl halides, that are used for the preparation of the before‐mentioned allyl derivatives. Here, we present a straightforward photocatalytic protocol for the decarboxylative allylation of oxime esters using allyl bromide derivatives under metal‐free and mild conditions. This methodology yields a diverse variety of functionalized molecules including several pharmaceutically relevant molecules.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Metal‐Free Decarboxylative Allylation of Oxime Esters under Light Irradiation ; day:09 ; month:07 ; year:2024 ; extent:6
Chemistry - a European journal ; (09.07.2024) (gesamt 6)

Urheber
Geniller, Lilian
Ben Kraim, Hiba
Clot, Eric
Taillefer, Marc
Jaroschik, Florian
Prieto, Alexis

DOI
10.1002/chem.202401494
URN
urn:nbn:de:101:1-2407101416399.078292336247
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:50 MESZ

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Beteiligte

  • Geniller, Lilian
  • Ben Kraim, Hiba
  • Clot, Eric
  • Taillefer, Marc
  • Jaroschik, Florian
  • Prieto, Alexis

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