Separation of Mixtures of Rutin and Quercetin: Evaluating the Productivity of Preparative Chromatography  

Abstract: The flavonoid rutin is present in significant amounts in the flower buds of Sophora japonica L. It offers numerous desired pharmacological effects. Under certain extraction conditions quercetin is found as a hydrolysis product which needs to be separated from rutin. This paper describes the application of liquid chromatography to solve this task. Based on the determination of adsorption equilibrium constants and column efficiencies, the productivity of the separation process is estimated, and scale‐up considerations are presented. A comparison with alternatively directly crystallizing rutin from raw extracts is also reported.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Separation of Mixtures of Rutin and Quercetin: Evaluating the Productivity of Preparative Chromatography   ; day:27 ; month:07 ; year:2023 ; extent:8
Chemie - Ingenieur - Technik ; (27.07.2023) (gesamt 8)

Creator
Vu, Tien Dinh
Selvasembian, Rangabhashiyam
Mutavdžin, Ivana
Horosanskaia, Elena
Lorenz, Heike
Seidel-Morgenstern, Andreas

DOI
10.1002/cite.202300050
URN
urn:nbn:de:101:1-2023072815083870965625
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:45 AM CEST

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Associated

  • Vu, Tien Dinh
  • Selvasembian, Rangabhashiyam
  • Mutavdžin, Ivana
  • Horosanskaia, Elena
  • Lorenz, Heike
  • Seidel-Morgenstern, Andreas

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