Anal Cancer in Systemic Lupus Erythematosus Patients is a Neglected Condition

Abstract: Patients with systemic lupus erythematosus have a higher incidence of neoplasms associated with human papillomavirus infections, such as those that affect the vulva, the vagina, and the cervix; however, little is known about the frequency of anal cancer among these patients. Although there are recommendations for screening for this cancer in immunosuppressed individuals, it is possible that this procedure is not strictly followed. We describe the case of a 47-year-old woman with systemic lupus erythematosus who was treated with immunosuppressants and developed advanced anal squamous cell carcinoma after adequate treatment and healing of a high-grade cervical squamous intraepithelial lesion. Five years after the completion of the anal cancer treatment, the patient presented with cystic hepatic lesions that were histopathologically confirmed to be metastatic squamous cell carcinoma. This report aimed to highlight the need for anal cancer screening in patients with lupus, particularly if there was a history of cervical cytopathological alterations.

Object Details

• Alternative title: Câncer anal em pacientes com lúpus eritematoso sistêmico é uma condição negligenciada
• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Anal Cancer in Systemic Lupus Erythematosus Patients is a Neglected Condition ; volume:43 ; number:01 ; year:2023 ; pages:052-055 ; Journal of coloproctology ; 43, Heft 01 (2023), 052-055

Contributors, Places and Time

• Contributor: Iamut, Maruska Dib ; Lacerda, Marcela Ignaccthiti ; Júnior, Mário Araújo ; Macedo, Jacyara Maria Brito ; Klumb, Evandro Mendes

Further information

• DOI: 10.1055/s-0042-1760220
• URN: urn:nbn:de:101:1-2023051110000883668486
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:54 AM CEST