Automatic detection of subviral particles in fluorescence microscopy images of Marburg virus infected cells using a convolutional neural network

Abstract: In collaboration with the Institute of Virology at the University of Marburg, a tracking algorithm has been developed in recent years. Thereby, for the tracking of subviral particles and their intracellular transport through the cell, the detection of these particles is the first major step. In this work a deep-learning based approach for automatic processing of fluorescence video sequences of virus infected cells is presented. The focus of this work was to generate synthetic data for training neuronal networks and to represent a particle using only a single delta peak. It was shown that a simple convolutional network is able to predict the particle positions with an almost identical accuracy as the algorithm developed by Kienzle, Rausch and colleagues [1-3], and that even a small dataset is sufficient for that purpose.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Automatic detection of subviral particles in fluorescence microscopy images of Marburg virus infected cells using a convolutional neural network ; volume:8 ; number:2 ; year:2022 ; pages:333-336 ; extent:4
Current directions in biomedical engineering ; 8, Heft 2 (2022), 333-336 (gesamt 4)

Urheber
Naber, Sarah
Busch, Nils
Rausch, Andreas
Schanze, Thomas

DOI
10.1515/cdbme-2022-1085
URN
urn:nbn:de:101:1-2022090315310778784380
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:31 MESZ

Datenpartner

Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.

Beteiligte

  • Naber, Sarah
  • Busch, Nils
  • Rausch, Andreas
  • Schanze, Thomas

Ähnliche Objekte (12)