Mitochondrial entry gate as regulatory hub
Abstract: Mitochondria import 1000–1300 different precursor proteins from the cytosol. The main mitochondrial entry gate is formed by the translocase of the outer membrane (TOM complex). Molecular coupling and modification of TOM subunits control and modulate protein import in response to cellular signaling. The TOM complex functions as regulatory hub to integrate mitochondrial protein biogenesis and quality control into the cellular proteostasis network
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Biochimica et biophysica acta. Molecular cell research. - 1871, 2 (2024) , 119529, ISSN: 1879-2596
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2023
- Creator
- DOI
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10.1016/j.bbamcr.2023.119529
- URN
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urn:nbn:de:bsz:25-freidok-2413158
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Brave, Fabian den
- Pfanner, Nikolaus
- Becker, Thomas
- Universität
Time of origin
- 2023