Mitochondrial entry gate as regulatory hub

Abstract: Mitochondria import 1000–1300 different precursor proteins from the cytosol. The main mitochondrial entry gate is formed by the translocase of the outer membrane (TOM complex). Molecular coupling and modification of TOM subunits control and modulate protein import in response to cellular signaling. The TOM complex functions as regulatory hub to integrate mitochondrial protein biogenesis and quality control into the cellular proteostasis network

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Biochimica et biophysica acta. Molecular cell research. - 1871, 2 (2024) , 119529, ISSN: 1879-2596

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2023
Creator

DOI
10.1016/j.bbamcr.2023.119529
URN
urn:nbn:de:bsz:25-freidok-2413158
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:28 AM CEST

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Associated

Time of origin

  • 2023

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