Infliximab-induced retrobulbar optic neuritis in a patient with ankylosing spondylitis

Abstract: Objective: To present a case with infliximab-induced retrobulbar optic neuritis.Case description: A 58-year-old woman presented to our clinic with a two-day history of blurred vision in her right eye. She had numerous uveitis attacks previously, and she was on infliximab treatment for ankylosing spondylitis. Her best-corrected visual acuity was counting fingers and 20/25 in the right and left eye, respectively. Optic discs seemed healthy in fundoscopic examination. The right optic nerve showed high signal intensity on magnetic resonance imaging (MRI). Infliximab treatment was discontinued and systemic steroid therapy was started. After the treatment her best-corrected visual acuity improved to 20/20 in her right eye.Conclusion: Infliximab is a chimeric human-murine monoclonal antibody used in autoimmune diseases. Optic neuritis is a rare but important side effect of infliximab. Thus, infliximab-induced optic neuritis should be kept in mind for patients receiving infliximab trea...

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Infliximab-induced retrobulbar optic neuritis in a patient with ankylosing spondylitis ; volume:13 ; day:12 ; month:12 ; year:2023 ; GMS ophthalmology cases ; 13 (12.12.2023)

Classification and Topics

• Classification: Medizin, Gesundheit

Contributors, Places and Time

• Creator: Dündar, Sema ; Yasar, Mimbay ; Çakmak, Harun ; Kiylioglu, Nefati ; Ünsal, Alparslan

Further information

• DOI: 10.3205/oc000232
• URN: urn:nbn:de:0183-oc0002324
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:31 AM CEST