Highly Efficient and Stereoselective Construction of Bispirooxindole Derivatives via a Three‐Component 1,3‐Dipolar Cycloaddition Reaction
Abstract: A highly regio‐ and stereoselective synthesis of bispirooxindoles by 1,3‐dipolar cycloaddition of in situ generated azomethine ylides from isatin and proline to different electron‐deficient alkenes has been developed. The synthesis affords the desired bispiro scaffold compounds in excellent yields with high regioselectivity under mild conditions. The stereochemistry was determined by single‐crystal X‐ray analysis.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Highly Efficient and Stereoselective Construction of Bispirooxindole Derivatives via a Three‐Component 1,3‐Dipolar Cycloaddition Reaction ; volume:3 ; number:3 ; year:2014 ; pages:93-98 ; extent:6
ChemistryOpen ; 3, Heft 3 (2014), 93-98 (gesamt 6)
- Creator
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Xu, Qin
Wang, De
Wei, Yin
Shi, Min
- DOI
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10.1002/open.201402003
- URN
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urn:nbn:de:101:1-2023011507523188094307
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:36 AM CEST
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Associated
- Xu, Qin
- Wang, De
- Wei, Yin
- Shi, Min
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