The Influence of Rheological and Wetting Properties of Hydrogel‐based Bio‐Inks on Extrusion‐based Bioprinting  

Abstract: The wall slip and flow behavior of alginate as well as gelatin based hydrogels with respect to the impact of these rheological and wetting properties on extrusion‐based bioprinting (EBB) was investigated. Capillary rheometry and printing tests indicate that slip is negligible at high stresses relevant for EBB, i.e., well above the hydrogels yield stress. On the contrary, rotational rheometry performed at low shear stresses revealed that alginate hydrogels present much stronger slip than gelatin gels, irrespective of crosslinker and polymer concentration. This result is presumably due to the formation of a heterogeneous microstructure for alginate gels and has an unfavorable impact on the printing quality with the production of large fluctuations in line width and higher line spread ratio.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
The Influence of Rheological and Wetting Properties of Hydrogel‐based Bio‐Inks on Extrusion‐based Bioprinting   ; day:04 ; month:01 ; year:2022 ; extent:10
Chemie - Ingenieur - Technik ; (04.01.2022) (gesamt 10)

Urheber
Maciel, Bruna Regina
Baki, Kubilay
Oelschlaeger, Claude
Willenbacher, Norbert

DOI
10.1002/cite.202100139
URN
urn:nbn:de:101:1-2022010514050479554493
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:25 MESZ

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Beteiligte

  • Maciel, Bruna Regina
  • Baki, Kubilay
  • Oelschlaeger, Claude
  • Willenbacher, Norbert

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