Synthesis of methyl 5-amino-3-arylaminoisoxazole-4-carboxylates

Abstract: The reaction of arylisothiocyanate derivatives with sodium methyl cyanoacetate in tetrahydrofuran gave the corresponding thioxo-propanoates, the reaction of which with hydroxylamine in ethanol and ammonium acetate under reflux conditions provided a synthetically useful method for the synthesis of methyl 5-amino-3-arylaminoisoxazole-4-carboxylates in good yields.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Synthesis of methyl 5-amino-3-arylaminoisoxazole-4-carboxylates ; volume:17 ; number:1-2 ; year:2011 ; pages:65-68
Heterocyclic communications ; 17, Heft 1-2 (2011), 65-68

Creator
Khalafy, Jabbar
Marjani, Ahmad Poursattar
Rostamzadeh, Ali

DOI
10.1515/hc.2011.014
URN
urn:nbn:de:101:1-2501140300032.718008677050
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:38 AM CEST

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Associated

  • Khalafy, Jabbar
  • Marjani, Ahmad Poursattar
  • Rostamzadeh, Ali

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