Adverse Effects Under Th2 Biologics (Dupilumab and Tezepelumab) in a Patient with Severe Asthma and Atopic Dermatitis

Introduction: This is the first report of a patient with severe asthma and atopic dermatitis that developed local perioral skin infection which onset coincided with the patient’s treatment with dupilumab (candida albicans) and later with tezepelumab (microscopic detection of yeast). Case Presentation: Besides moderate headache, macular exanthema was found after administration of tezepelumab, which was subsequently accompanied by a worsening of symptoms upon reexposure to the treatment. Both sensations needed multidisciplinary treatment and both antibody therapies were stopped.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Adverse Effects Under Th2 Biologics (Dupilumab and Tezepelumab) in a Patient with Severe Asthma and Atopic Dermatitis ; volume:102 ; number:12 ; year:2023 ; pages:1016-1019 ; extent:4 ; Respiration ; 102, Heft 12 (2023), 1016-1019 (gesamt 4)

Contributors, Places and Time

• Creator: Suhling, Hendrik ; Hinze, Christopher Alexander ; Welte, Tobias ; Werfel, Thomas ; Traidl, Stephan

Further information

• DOI: 10.1159/000534924
• URN: urn:nbn:de:101:1-2023122801191989473210
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:33 AM CEST