Recent process of using nanoparticles in the T cell-based immunometabolic therapy

Abstract: Immunotherapy is currently the main treatment for malignant tumors by activating immune cell. Metabolic reprogramming in tumor microenvironment can greatly affect the function of immune cell, and T cell is the main anti-tumor effector cell. Therefore, the T cell-based immunometabolic therapy can improve clinical efficacy. In T cell-based immunometabolic therapy, regular agents in conventional forms are difficult to achieve the intended efficacy due to poor tumor permeability and low cellular uptake. Nanoparticle-based strategy can serve as the optimal targeted drug delivery system due to co-encapsulation of multiple therapeutic agents and stable loading. Here, we intend to summarize examples of nanoparticles in the T cell-based immunometabolic therapy, and provide a comprehensive and helpful review by covering notable and vital applications of nanotechnology-based strategies for T cell-based immunometabolic therapy.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Recent process of using nanoparticles in the T cell-based immunometabolic therapy ; volume:13 ; number:1 ; year:2024 ; extent:12
Nanotechnology reviews ; 13, Heft 1 (2024) (gesamt 12)

Creator
Chen, Bingxin
Li, Yangyang
Wang, Hui

DOI
10.1515/ntrev-2024-0072
URN
urn:nbn:de:101:1-2409241605327.204775639333
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:28 AM CEST

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Associated

  • Chen, Bingxin
  • Li, Yangyang
  • Wang, Hui

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