Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

to related objects

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: 1 Online-Ressource.

Language: Englisch

Bibliographic citation: Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells ; volume:15 ; number:1 ; day:2 ; month:1 ; year:2024 ; pages:1-14 ; date:12.2024
Nature Communications ; 15, Heft 1 (2.1.2024), 1-14, 12.2024

Creator: Baik, Ron
Cromer, M. Kyle
Glenn, Steve E.
Vakulskas, Christopher A.
Chmielewski, Kay O.
Dudek, Amanda M.
Feist, William N.
Klermund, Julia
Shipp, Suzette
Cathomen, Anton
Dever, Daniel P.
Porteus, Matthew H.

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41467-023-43413-w

URN: urn:nbn:de:101:1-2024031509400303093857

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 11:00 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Baik, Ron
Cromer, M. Kyle
Glenn, Steve E.
Vakulskas, Christopher A.
Chmielewski, Kay O.
Dudek, Amanda M.
Feist, William N.
Klermund, Julia
Shipp, Suzette
Cathomen, Anton
Dever, Daniel P.
Porteus, Matthew H.
SpringerLink (Online service)

Other Objects (12)

Hochschulschrift

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Hochschulschrift

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

Aufsatzsammlung

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Hochschulschrift

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Hochschulschrift

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

Aufsatzsammlung

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Hochschulschrift

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Hochschulschrift

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

Aufsatzsammlung

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Establishing a zinc finger nuclease platform for targeted genome editing in human cell lines, primary keratinocyte stem cells and cardiomyocytes in vivo

Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells

Targeted gene transfer to enhance safety and efficacy of immunotherapy

Entwicklung von gentechnologischen Strategien zur Überwindung der Bluthirnschranke am Modell des Morbus Gaucher Typ 2

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

CRISPR/Cas9 - einschneidende Revolution in der Gentechnik

Clinical genome editing to treat sickle cell disease - a brief update

Generation of safe CAR T cells to target B cell malignancies

Targeted integration of a super-exon into the CFTR locus leads to functional correction of a cystic fibrosis cell line model

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Chimerization enables gene synthesis and lentiviral delivery of customizable TALE-based effectors

Related objects

Reset password