Ischemic Hepatitis and Septic Shock Secondary to Murine Typhus Infection in Pregnancy

Abstract: Infection with murine typhus may be associated with significant morbidity. With nonspecific symptoms and laboratory abnormalities, diagnosis may be challenging. In this case, a pregnant patient presented with complaints of fevers and myalgias. Her laboratory results included severe transaminitis as well as thrombocytopenia and hyponatremia. She ultimately required vasopressor support and intensive care unit admission despite fluid resuscitation and broad-spectrum antibiotics. Empiric doxycycline was initiated due to suspicion for murine typhus, which laboratory testing later confirmed. Her clinical status improved with these interventions. This was a severe case of murine typhus resulting in septic shock and ischemic hepatitis. It is important to know the typical findings of murine typhus and consider it in a differential diagnosis, especially when practicing in endemic areas.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Ischemic Hepatitis and Septic Shock Secondary to Murine Typhus Infection in Pregnancy ; volume:14 ; number:02 ; year:2024 ; pages:e185-e187
AJP reports ; 14, Heft 02 (2024), e185-e187

Contributor
Berry, Marissa
Wang, Amanda M.
Lahham, Rana F.
Zhang, Xue
Pacheco, Luis D.

DOI
10.1055/a-2330-4249
URN
urn:nbn:de:101:1-2407251105322.331164741401
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:48 AM CEST

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Associated

  • Berry, Marissa
  • Wang, Amanda M.
  • Lahham, Rana F.
  • Zhang, Xue
  • Pacheco, Luis D.

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