9‐Membered Carbocycles: Strategies and Tactics for their Synthesis
Abstract: Many natural products comprising a nine‐membered carbocyclic core structure exhibit interesting biological effects. However, only a minority have succumbed to their synthesis in the past. The synthesis of functionalized nine‐membered carbocycles still remains a challenging goal for synthetic chemists, mainly due to their high ring strain. Different strategies to overcome the unfavorable enthalpic and entropic factors associated with their formation are highlighted in this Concept article. The presented methods are classified into two different categories: (1) the ring‐expansion of smaller rings or the ring‐contraction of larger rings and (2) the direct cyclization of acyclic precursors.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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9‐Membered Carbocycles: Strategies and Tactics for their Synthesis ; volume:24 ; number:47 ; year:2018 ; pages:12107-12120 ; extent:14
Chemistry - a European journal ; 24, Heft 47 (2018), 12107-12120 (gesamt 14)
- Creator
- DOI
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10.1002/chem.201705919
- URN
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urn:nbn:de:101:1-2022090207223990358528
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:20 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Huber, Tatjana
- Wildermuth, Raphael E.
- Magauer, Thomas
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