Stabilized Carbon Radical‐Mediated Assembly of Arylthianthrenium Salts, Alkenes and Amino Acid/Peptide Derivatives

to related objects

Abstract: Efficiently assembling amino acids and peptides with bioactive molecules facilitates the modular and streamlined synthesis of a diverse library of peptide‐related compounds. Particularly notable is their application in pharmaceutical development, leveraging site‐selective late‐stage functionalization. Here, a visible light‐induced three‐component reaction involving arylthianthrenium salts, amino acid/peptide derivatives, and alkenes are introduced. This approach utilizes captodatively‐stabilized carbon radicals to enable radical‐radical C─C coupling, effectively constructing complex bioactive molecules. This method offers a promising alternative route for modular synthesis of peptide‐derived bio‐relevant compounds

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: Stabilized Carbon Radical‐Mediated Assembly of Arylthianthrenium Salts, Alkenes and Amino Acid/Peptide Derivatives ; day:21 ; month:11 ; year:2024 ; extent:8
Advanced science ; (21.11.2024) (gesamt 8)

Creator: Dong, Bo
Qi, Weiguan
Chen, Yifeng
Zhang, Yufei
Gu, Shiyu
Zhao, Jianlin
Zhou, Qingfa
Shen, Jian
Xie, Lan‐Gui

DOI: 10.1002/advs.202411579

URN: urn:nbn:de:101:1-2411221404178.026916371352

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:20 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Dong, Bo
Qi, Weiguan
Chen, Yifeng
Zhang, Yufei
Gu, Shiyu
Zhao, Jianlin
Zhou, Qingfa
Shen, Jian
Xie, Lan‐Gui

Other Objects (12)

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Hochschulschrift

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Hochschulschrift

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Hochschulschrift

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read and agree to the privacy policy for the collection of personal data.*

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Stabilized Carbon Radical‐Mediated Assembly of Arylthianthrenium Salts, Alkenes and Amino Acid/Peptide Derivatives

Show object

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Asymmetric Radical Cyclopropanation of Alkenes

Radical‐Mediated Hydroperfluoroalkylation of Unactivated Alkenes

Cobalt-catalyzed aminoalkylative carbonylation of alkenes toward direct synthesis of γ-amino acid derivatives and peptides

Radical 1‐Fluorosulfonyl‐2‐alkynylation of Unactivated Alkenes

Synthesis of Unnatural α‐Amino Acid Derivatives via Light‐Mediated Radical Decarboxylative Processes

Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes

Stabilized Carbon‐Centered Radical‐Mediated Carbosulfenylation of Styrenes: Modular Synthesis of Sulfur‐Containing Glycine and Peptide Derivatives

ISOQUINOLINE-BASED AMINO ACID DERIVATIVES

Amino-quat-primer polymer stabilized silica-nanoparticle-dispersions

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Carboamination of Unactivated Alkenes through Three‐Component Radical Conjugate Addition

Related objects

Reset password