Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
1 Online-Ressource.
- Language
-
Englisch
- Bibliographic citation
-
Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine physiology in VPS35 p.D620N knock-in mice ; volume:9 ; number:1 ; day:18 ; month:12 ; year:2023 ; pages:1-12 ; date:12.2023
npj Parkinson's Disease ; 9, Heft 1 (18.12.2023), 1-12, 12.2023
- Creator
-
Bu, Mengfei
Follett, Jordan
Deng, Isaac
Tatarnikov, Igor
Wall, Shannon
Guenther, Dylan
Maczis, Melissa
Wimsatt, Genevieve
Milnerwood, Austen
Moehle, Mark S.
Khoshbouei, Habibeh
Farrer, Matthew J.
- Contributor
-
SpringerLink (Online service)
- DOI
-
10.1038/s41531-023-00609-7
- URN
-
urn:nbn:de:101:1-2024030220594970631827
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
14.08.2025, 10:58 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Bu, Mengfei
- Follett, Jordan
- Deng, Isaac
- Tatarnikov, Igor
- Wall, Shannon
- Guenther, Dylan
- Maczis, Melissa
- Wimsatt, Genevieve
- Milnerwood, Austen
- Moehle, Mark S.
- Khoshbouei, Habibeh
- Farrer, Matthew J.
- SpringerLink (Online service)
Other Objects (12)
LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease
R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
Knock, Knock, Knockin’ on Tranformativeness’ Doors
Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model
Conditional Knock-in and -out, VW-Antrag
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition
Ackr3-Venus knock-in mouse lights up brain vasculature
Ubap1 knock-in mice reproduced the phenotype of SPG80
Tracing connexin-26 expression using a genetic "knock-in" approach
A robust TDP-43 knock-in mouse model of ALS
P53 functional studies with hupki (human p53 knock-in) mouse model
NR 1 Knock-in mice (Oslo letters), NR1-Q, NR1-R
LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease
R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
Knock, Knock, Knockin’ on Tranformativeness’ Doors
Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model
Conditional Knock-in and -out, VW-Antrag
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition
Ackr3-Venus knock-in mouse lights up brain vasculature
Ubap1 knock-in mice reproduced the phenotype of SPG80
Tracing connexin-26 expression using a genetic "knock-in" approach
A robust TDP-43 knock-in mouse model of ALS
P53 functional studies with hupki (human p53 knock-in) mouse model
NR 1 Knock-in mice (Oslo letters), NR1-Q, NR1-R
LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease
R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
Knock, Knock, Knockin’ on Tranformativeness’ Doors
Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model
Conditional Knock-in and -out, VW-Antrag
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition
Ackr3-Venus knock-in mouse lights up brain vasculature
Ubap1 knock-in mice reproduced the phenotype of SPG80
Tracing connexin-26 expression using a genetic "knock-in" approach
A robust TDP-43 knock-in mouse model of ALS
P53 functional studies with hupki (human p53 knock-in) mouse model