Scalable Electrochemical Decarboxylative Olefination Driven by Alternating Polarity **

Abstract: A mild, scalable (kg) metal‐free electrochemical decarboxylation of alkyl carboxylic acids to olefins is disclosed. Numerous applications are presented wherein this transformation can simplify alkene synthesis and provide alternative synthetic access to valuable olefins from simple carboxylic acid feedstocks. This robust method relies on alternating polarity to maintain the quality of the electrode surface and local pH, providing a deeper understanding of the Hofer‐Moest process with unprecedented chemoselectivity.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Scalable Electrochemical Decarboxylative Olefination Driven by Alternating Polarity ** ; day:13 ; month:09 ; year:2023 ; extent:8 ; Angewandte Chemie / International edition. International edition ; (13.09.2023) (gesamt 8)

Contributors, Places and Time

• Creator: Garrido‐Castro, Alberto F. ; Hioki, Yuta ; Kusumoto, Yoshifumi ; Hayashi, Kyohei ; Griffin, Jeremy ; Harper, Kaid C. ; Kawamata, Yu ; Baran, Phil S.

Further information

• DOI: 10.1002/anie.202309157
• URN: urn:nbn:de:101:1-2023091316023293628225
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 11:01 AM CEST