Hyposplenism and Gastrointestinal Diseases: Significance and Mechanisms

Background: Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders. Summary: The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management. Key Messages: Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Hyposplenism and Gastrointestinal Diseases: Significance and Mechanisms ; volume:40 ; number:3 ; year:2022 ; pages:290-298 ; extent:9
Digestive diseases ; 40, Heft 3 (2022), 290-298 (gesamt 9)

Creator
Mathur, Abhinav
McLean, Mairi H.
Cao, Huan
Vickers, Mark A.

DOI
10.1159/000517338
URN
urn:nbn:de:101:1-2022051900182291575981
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:25 AM CEST

Data provider

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Associated

  • Mathur, Abhinav
  • McLean, Mairi H.
  • Cao, Huan
  • Vickers, Mark A.

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