Acid‐Catalyzed Carbene Transfer from Diazo Compounds: Carbocation versus Carbene as Key Intermediate
Abstract: An efficient mechanism for the acid‐catalyzed formal carbene transfer from diazo compounds to nucleophilic substrates is disclosed by DFT calculations. In sharp contrast to recent proposal via neutral carbene‐like intermediates, the new mechanism involves selective diazo C‐protonation to form catalytic electrophilic carbocations, thus enabling a broad choice of metal‐free acid catalysts and nucleophilic substrates.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Acid‐Catalyzed Carbene Transfer from Diazo Compounds: Carbocation versus Carbene as Key Intermediate ; volume:2022 ; number:17 ; year:2022 ; extent:4
European journal of organic chemistry ; 2022, Heft 17 (2022) (gesamt 4)
- Creator
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Qu, Zheng‐Wang
Zhu, Hui
Grimme, Stefan
- DOI
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10.1002/ejoc.202200408
- URN
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urn:nbn:de:101:1-2022050215310610109425
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:22 AM CEST
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Associated
- Qu, Zheng‐Wang
- Zhu, Hui
- Grimme, Stefan
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