Julia‐Kocienski‐Like Connective C−C and C=C Bond‐Forming Reaction
Abstract: In this paper, we present a one‐pot protocol that enables a straightforward and selective transformation of alkyl benzothiazol‐2‐yl and phenyltetrazol‐2‐yl sulfones and acyl chlorides into ketones, E‐olefins, Z‐olefins, and even pyrroles. The final product of the reaction depends on the proper choice of the reaction workup. Notably, the protocol designed for olefin formation allows a switch between E‐ and Z‐olefin formation by the correct choice of the reaction workup. These developed protocols facilitate the formation of all compounds under mild reaction conditions, as evidenced by the synthesis of (nitro)‐fatty acids, and the concept can be extended to other product formations, as demonstrated by the synthesis of pyrroles.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Julia‐Kocienski‐Like Connective C−C and C=C Bond‐Forming Reaction ; day:07 ; month:01 ; year:2024 ; extent:9
Advanced synthesis & catalysis ; (07.01.2024) (gesamt 9)
- Creator
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Bon, David J.‐Y. D.
Chrenko, Daniel
Kováč, Ondřej
Ferugová, Vendula
Lasák, Pavel
Fuksová, Markéta
Zálešák, František
Pospíšil, Jiří
- DOI
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10.1002/adsc.202301054
- URN
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urn:nbn:de:101:1-2024010814145556183002
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:34 AM CEST
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Associated
- Bon, David J.‐Y. D.
- Chrenko, Daniel
- Kováč, Ondřej
- Ferugová, Vendula
- Lasák, Pavel
- Fuksová, Markéta
- Zálešák, František
- Pospíšil, Jiří
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Iridium-Catalyzed C–C Bond-Forming Transfer Hydrogenation
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Development of new catalytic C-C bond forming and hydrogenation reactions
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Development of Nickel-catalyzed C-C bond forming reactions and catalytic enantioselective trifluoromethylthiolations
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