The SELUTION SLR™ drug-eluting balloon system for the treatment of symptomatic femoropopliteal lesions

Abstract: Endovascular treatment has become first line therapy for the treatment of femoropopliteal disease. Drug-coated devices play a key role in maintaining vessel patency. In the past antiproliferative coating of drug-coated balloons (DCBs) exclusively consisted of paclitaxel. Use of limus drugs was limited by a short residency time in the vessel wall. Besides the drug, the SELUTION SLR™ drug-eluting balloon system consists of a coating formulation of four excipients. The first excipient is a biodegradable polymer (poly(lactic-co-glycolic acid)) that is intermixed with the sirolimus to form micro-reservoirs and regulates drug release via matrix degradation. This review summarizes the existing pre-clinical and clinical literature on treatment of femoropopliteal artery lesions with the SELUTION SLR DCB

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Future cardiology. - 17, 2 (2021) , 257–267, ISSN: 1744-8298

Keyword
Sirolimus

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2020

DOI
10.2217/fca-2020-0085
URN
urn:nbn:de:bsz:25-freidok-1678859
Rights
Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:54 PM CET

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Time of origin

  • 2020

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